September 8

Natural Alternatives to Ozempic (Wegovy & Semaglutide) | Research & WARNINGS!


Ozempic has been all over the news–and the TV advertisements–for a few months now. As a fitness guide and writer, I’ve been skeptical, to say the least, about this diabetes medication for weight loss. Using a medication for a reason it wasn’t authorized for, even when it’s prescribed to you, is called an “off-label use.” 

Now, I’m not going to gainsay anyone’s doctor–if your doctor has prescribed something to you, do not stop taking it before talking to them extensively, first. But if you are simply considering taking Ozempic for weight loss, and not for any other diagnosed condition, read this article first! It could save you time, money, and more importantly, you might find a better path toward losing weight and cutting fat. 

NOTE: This article is not intended to help diagnose, treat, or cure any disease or disorder. If you have a prescription for Ozempic or similar medication, consult your physician before making any changes to your supplement or medication routine.

What is Ozempic?

Ozempic is what’s called a semaglutide, and it has been prescribed as a Diabetes medication for decades. It is a synthetic, or man made chemical that mimics the natural hormone in our body, Glucagon-like Peptide-1, or GLP-1 for short. GLP-1 is a natural hormone in our digestive tracts. When it senses that we’ve eaten, it sends signals to our Pancreas to release Insulin. (More on Insulin in a bit.)

Ozempic, and other semaglutide, are called GLP-1 receptor agonists. Essentially, they trigger the release of GLP-1 even when we haven’t eaten. For diabetics, this drug was a game-changer. They could now rely on their body’s own processes to produce more insulin, without having to take insulin injections.

For overweight and obese people, and how Ozempic helps them, we have to take a quick detour into what Insulin is, and how it impacts weight loss.

Insulin, Ozempic, and Weight Loss

In a future article I may break down this process in more detail. But for now, here’s the quick version of how Insulin and Weight Loss are related.

When we ingest sugar–or any food that converts to sugar–that sugar enters into our bloodstream. Simultaneous to that, when we eat our bodies release the GLP-1 I mentioned. This tells our Pancreas to release insulin. Insulin then goes to all the cells in our body and tells them to pick the sugar up out of our blood stream.

If our pancreas doesn’t produce Insulin, or if our cells are resistant to the Insulin signal, then the sugar stays in our bloodstream. And eventually, it turns into triglycerides–that is, fat.

Any disruption in any of those processes means our bodies don’t burn sugar correctly, and we gain weight as fat around our bodies. Thus, anything that can support those processes, like Ozempic, can theoretically lead to weight loss.

Moreover, recent studies have shown that in non-diabetic people, higher doses of semaglutide can block appetite by helping people feel more full.


If all that sounds a bit scientific, that’s because it is. And don’t forget, semaglutide is a synthetic drug. Not only is it not natural, but you need a prescription to obtain it, and even then, it can run you hundreds of dollars a month

That’s one main reason I’m writing this article. To help you make an informed decision as you’re researching your weight loss options. So without further ado, here are the best alternatives to Ozempic–they’re all safe, they’re all prescription free. They’re all affordable, and they all work!

PhenQ – Best Overall

PhenQ is more than just the best alternative to Ozempic for weight loss–it may be the absolute best weight-loss option on the market, period. It doesn’t matter if you have a naturally slow metabolism, if you struggle with eating habits, or if you don’t even know where to start with your weight loss. PhenQ and its unique ingredient α-Lacys Reset has you covered.

Why PhenQ is Number One

Starting with the novel compound α-Lacys Reset, PhenQ’s formula includes fat-burning ingredients, appetite suppressants, vital nutrients, and a bit of caffeine to jumpstart your weight loss. In short, PhenQ is Number One because it has everything you need to lose weight.  

Pros and Cons


  • Multiple proven fat-burning ingredients, like L-Carnitine and Capsaicin.
  • Four separate appetite suppressants to combat snacking no matter what the cause of the craving.
  • 60-Day Money Back Guarantee.
  • Only supplement on the list with α-Lacys Reset.


  • Best prices are only available with large orders.
  • Caffeine levels may be too high for some users.

How it Works

PhenQ is designed to work both immediately, to get your fitness journey off to a fast start, and to keep working over time. To begin with, the 100 mg of Capsimax get your thermogenesis started right, and it begins blocking your appetite that same day. The α-Lacys Reset also gets to work right off, helping both suppress food cravings, and to begin lowering your blood sugar right away.

While your blood sugar continues to go down–a key to weight loss we saw above–long-term fat-burning begins to set in over the next few weeks. And it never stops. Long-term studies have shown that use of the ingredients in PhenQ, like Nopal Cactus, continue to produce weight loss over time

Last Word

If you have time, check out my full review of PhenQ here. Otherwise, you can simply move on to checking out their website. Not only is it a fraction of the price of Ozempic, but it comes with a money-back guarantee. Combine that with how well researched its proven ingredients are, and it’s easy to see how it consistently rates number one in all my reviews.

Leanbean – Best for Women

Sometimes we want something made just for us, not the one-size-fits all supplements. If that’s the case, the next two options are for you. The first, Leanbean, is a weight loss supplement predicated on the concept that a woman’s body needs different things than a man’s body. Beginning with a healthy dose of the proven appetite suppressant Glucomannan, Leanbean follows up their formula with sure-fire winners. Let’s jump in. 

Pros and Cons


  • Absolute best weight loss supplement made just for women!
  • Made with Glucomannan and two forms of antioxidants for whole-body wellness.
  • Low caffeine, so it won’t disrupt your daily routines.


  • May not be ideal for men; for that, skip to the next alternative, Capsiplex.
  • Doesn’t have quite as many thermogenic ingredients as other supplements.

How it Works

Leanbean operates under the principle that your body has all the right functions already, it could just use a little help. With that in mind, they’ve chosen Glucomannan, a soluble fiber from the Konjac Root, which can regulate blood sugar and increase your calorie burn. Two things Ozempic can do, only Leanbean does it naturally. 

Next, they’ve included the powerful antioxidant Acai Berry and Green Coffee bean, which scientific research has indicated can be a powerful fat-burner. So while Leanbean is helping you eat less, it’s also helping with that pesky blood sugar, and then helping you burn fat more efficiently. And all designed to work with a woman’s unique body chemistry, not against it. 

Last Word

It comforts some women to know that what they’re putting in their body was made just for them. If that’s the case for you, then look no further than Leanbean. If you want to know more about it, check out my full review here

Capsiplex Burn – Best for Men

Capsiplex does for men what Leanbean does for women. It’s curated for the man’s body, to work with our natural testosterone-fueled body functions, and to literally melt the fat off of you. 

Pros and Cons


  • High-octane fat-shredder with one of the highest doses of Capsaicin on the market. 
  • Green Tea and Green Coffee Extracts for caffeine, chlorogenic acid, and catechins.
  • Amino acids and essential minerals for fat-burning and muscle-building.


  • Not at all a good fit for women; for that, go back up to Leanbean.
  • Extremely high caffeine content, which is not good for some people.

How it Works

Capsiplex works on the idea that you’re already working out and dieting, and you just need that one last push from behind to get you over the finish line. To that end, they’ve got 100 mg of Capsimax, 200 mg of Caffeine Anhydrous, and two Amino Acids to rocket your workouts into the highest gear. The appetite suppressing qualities are all from natural Chromium and Iodine, meaning no bloating to interfere with your high-intensity gym sessions.

Last Word

Capsiplex Burn is definitely not for everyone. It’s an acute fat-burner that really works well for men who are already in the gym, and who want to keep their muscle mass. It’s also best for people who aren’t afraid of a big jolt of energy. If that’s you, Capsiplex could be your number one option.

PhenQ PM – Best for Night Time

A night time fat-burner? That’s right. And no, it’s not too good to be true. PhenQ PM really does work to burn fat and control your appetite–all while you sleep. It’s a great option for people who don’t want anything caffeinated during the day, or with a fiber that could bloat them. It’s also ideal for people who already have a favorite day time supplement, and want to add another for 24-hour support.

Pros and Cons


  • No stimulants, no fibers. That means you can rest and rest easily.
  • Supports healthy sleep mental health with Molybdenum and L-Arginine.
  • Mineral-supported appetite suppression that works with your body to keep you asleep.


  • Won’t help with workouts or daytime snacking the way other supplements do.
  • Anyone taking medications for sleep needs to talk to their doctor before trying PhenQ PM.

How it Works

PhenQ PM comes at weight loss from the understanding that how the day ahead will go owes largely to how the night before went. Study after study has shown us that the better we sleep, the more weight we lose. So PhenQ PMs formula is designed around helping us get to sleep, stay asleep, and wake up with a little bit of fat-burned off in the meantime.

Last Word

The science behind PhenQ PM is really quite fascinating. If you’re interested, I have a full explanation of it all here. In any case, if you’re looking for a supplementary supplement (sorry, I had to) then PhenQ PM is nearly the only supplement on the market specifically made for night time use; and it’s the only one I’ve found I trust enough to stack up against any day time formulas.

Instant Knockout – Best for Active People

The last entry on the list is sort of a combination of philosophies. Instant Knockout has taken the Glucomannan from Leanbean, the Caffeine and Capsaicin from PhenQ and Capsiplex, and combined it all with a similar calming ingredient from PhenQ PM. It’s ideal for people who are on the go–so need the caffeine Leanbean lacks–but who also want help with the mood spikes that a hectic life and caffeine can exacerbate.

Pros and Cons


  • Well-rounded formula with proven ingredients.
  • Caffeinated for people who need energy throughout a busy day.
  • Great for long-term benefits.


  • Not as focused as the other entries on the list.
  • Caffeine-sensitive people should look elsewhere on the list.

How it Works

Instant Knockout starts out like Leanbean–with a large dose of Glucomannan to help reduce cravings and calorie absorption. From there, though, Knockout helps take your body into high-energy mode with Capsaicin and Caffeine, promoting thermogenesis and helping keep your appetite from flaring up. Lastly, the L-Theanine from Green Tea can help you concentrate on your tasks–like that workout!–but can also help keep your mood balanced and even.

Last Word

Instant Knockout isn’t tailor made for women or men, and doesn’t have the unique ingredients of PhenQ. But it is a great weight loss supplement for people who like the best-of-all-worlds approach.

Final Thoughts

Ozempic is a proven, well-trusted medicine for people with Diabetes. In its long history, people have found that it can massively reduce waistlines and body fat. But it can also run you nearly $1,000 a month. And it requires a prescription, it does come with a warning label, and it isn’t natural.

Many of the alternatives here are 100% natural, and every single one of them is safe and effective. For more information, check out the links to my reviews. And as always, do what’s best for your health and your unique lifestyle. 



PhenQ is designed for everyone, no matter where you are on your weightloss journey. It can help someone who only needs to lose the last 15 pounds for their goal, and it can also be a giant help for folks just getting started.


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